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杨晓明
发布时间2013-08-02 03:25:54     作者:    浏览次数: 次

1、个人概况

杨晓明                  

出生年月:19821

籍贯:山西怀仁

职称:教授,硕士生导师

学位:理学博士

邮箱xiaomingyang4444@126.com

 

2、教育及工作经历

2010-至今    西南大学药学院

2007-2009    四川大学-美国普渡大学                              理学博士

2004-2007    四川大学化学学院                                     硕博连读

2000-2004    四川大学化学学院                                     理学学士

 

3、研究方向

(1) 药物分析方法学研究:荧光纳米材料合成方法和机制的探索、表征及其在药物分析、疾病标志物检测中的应用。

(2) 免疫分析方法学研究:基于荧光纳米材料、结合免疫分析,建立针对药物、细菌、环境中小分子的检测方法。

(3) 探究潜在肿瘤标志物Plk1及相关蛋白激酶在癌细胞信号通路中的功能:细胞增殖与调控,细胞信号转导。

4、发表学术论文

1. Dan Zhong, Kuncheng Yang, Yingyi Wang, Xiaoming Yang*. Dual-channel sensing strategy based on gold nanoparticles cooperating with carbon dots and hairpin structure for assaying RNA and DNA. Talanta, 2017, 175:217-223. (SCI, IF=4.162)

2. Kuncheng Yang, Mingxu Liu, Yingyi Wang, Shanshan Wang, Hong Miao, Liqun Yang*, Xiaoming Yang*. Carbon dots derived from fungus for sensing hyaluronic acid and hyaluronidase. Sensors and Actuators B: Chemical, 2017, 251:503-508. (SCI, IF=5.401)

3. Kuncheng Yang, Shanshan Wang, Yingyi Wang, Hong Miao, Xiaoming Yang*. Dual-channel probe of carbon dots cooperating with gold nanoclusters employed for assaying multiple targets. Biosensors and Bioelectronics, 2017, 91:566-573. (SCI, IF=7.780)

4. Hong Miao, Lan Wang, Yan Zhuo, Zinan Zhou, Xiaoming Yang*. Label-free fluorimetric detection of CEA using carbon dots derived from tomato juice. Biosensors and Bioelectronics, 2016, 86:83-89. (SCI, IF=7.780)

5. Hong Miao, Yuanjiao Feng, Dan Zhong, Xiaoming Yang*. Enhanced-fluorescence of europium-copper nanoclusters for cell imaging. Journal of Materials Science, 2016, 51:7229-7235. (SCI, IF=2.599)

6. Zhangbao Chen, Jing Wang, Hong Miao, Lan Wang, Shuang Wu & Xiaoming Yang*. Fluorescent carbon dots derived from lactose for assaying folic acid. Science China-Chemistry, 2016, 59:487-492. (SCI, IF=4.132)

7. Dan Zhong, Hong Miao, Kuncheng Yang, Xiaoming Yang*. Carbon dots originated from carnation for fluorescent and colorimetric pH sensing. Materials Letters, 2016, 166:89-92. (SCI, IF=2.572)

8. Lan Wang, Hong Miao, Dan Zhong and Xiaoming Yang*. Synthesis of dopamine-mediated Cu nanoclusters for sensing and fluorescent coding. Analytical Methods, 2016, 8:40-44. (SCI, IF=1.900)

9. Hong Miao, Dan Zhong, Zinan Zhou and Xiaoming Yang*. Papain-templated Cu nanoclusters: assaying and exhibiting dramatic antibacterial activity cooperating with H2O2. Nanoscale, 2015, 7:19066-19072. (SCI, IF=7.367)

10. Shanshan Zhu, Yan Zhuo, Hong Miao, Dan Zhong and Xiaoming Yang*. Detection of mercury(II) by DNA templated gold nanoclusters based on forming thymidine-Hg2+-thymidine duplexes. Luminescence, 2015, 30:631-636. (SCI, IF=1.509)

11. Dan Zhong, Yan Zhuo, Yuanjiao Feng, Xiaoming Yang*. Employing carbon dots modified with vancomycin for assaying Gram-positive bacteria like Staphylococcus aureus. Biosensors and Bioelectronics, 2015, 74:546-553. (SCI, IF=7.780)

12. Yawen Luo, Hong Miao, Xiaoming Yang*. Glutathione-stabilized Cu nanoclusters as fluorescent probes for sensing pH and vitamin B1. Talanta, 2015, 144:488-495. (SCI, IF=4.162)

13. Yan Zhuo, Dan Zhong, Hong Miao and Xiaoming Yang*. Reduced carbon dots employed for synthesizing metal nanoclusters and nanoparticles. RSC Advances, 2015, 5:32669-32674.  (SCI, IF=3.108)

14. Yuanjiao Feng, Dan Zhong, Hong Miao, Xiaoming Yang*. Carbon dots derived from rose flowers for tetracycline sensing. Talanta, 2015, 140:128-133. (SCI, IF=4.162)

15. Yan Zhuo, Hong Miao, Dan Zhong, Shanshan Zhu, Xiaoming Yang*. One-step synthesis of high quantum-yield and excitation-independent emission carbon dots for cell imaging. Materials Letters, 2015, 139:197-200. (SCI, IF=2.572)

16. Xiaoming Yang*, Yan Zhuo, Shanshan Zhu, Yawen Luo, Yuanjiao Feng, Yan Xu. Selectively assaying CEA based on a creative strategy of gold nanoparticles enhancing silver nanoclusters’ fluorescence. Biosensors and Bioelectronics, 2015, 64:345-351. (SCI, IF=7.780)

17. Xiaoming Yang*, Yuanjiao Feng, Shanshan Zhu, Yawen Luo, Yan Zhuo, Yao Dou. One-step synthesis and applications of fluorescent Cu nanoclusters stabilized by L-Cysteine in aqueous solution. Analytica Chimica Acta, 2014, 847:49-54. (SCI, IF=4.950)

18. Xiaoming Yang*, Yawen Luo, Yan Zhuo, Yuanjiao Feng, Shanshan Zhu. Novel synthesis of gold nanoclusters templated with L-tyrosine for selective analyzing tyrosinase. Analytica Chimica Acta, 2014, 840:87-92. (SCI, IF=4.950)

19. Xiaoming Yang*, Yan Zhuo, Shanshan Zhu, Yawen Luo, Yuanjiao Feng, Yao Dou. Novel and green synthesis of high-fluorescent carbon dots originated from honey for sensing and imaging. Biosensors and Bioelectronics, 2014, 60:292-298. (SCI, IF=7.780)

20. Yan Xu, Xiaoming Yang*, Shanshan Zhu, Yao Dou. Selectively fluorescent sensing of Cu2+ based on Lysine-functionalized gold nanoclusters. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 450: 115-120. (SCI, IF=2.714)

21. Xiaoming Yang*, Yawen Luo, Shanshan Zhu, Yuanjiao Feng, Yan Zhuo, Yao Dou. One-pot synthesis of high fluorescent carbon nanoparticles and their applications as probes for detection of tetracyclines. Biosensors and Bioelectronics, 2014, 56: 6-11.(SCI, IF=7.780)

22. Xiaoming Yang*, Shanshan Zhu, Yao Dou, Yan Zhuo, Yawen Luo, Yuanjiao Feng. Novel and remarkable enhanced-fluorescence system based on gold nanoclusters for detection of tetracycline. Talanta, 2014, 122: 36-42. (SCI, IF=4.162)

23. Xiaoming Yang*, Lei Yang, Yao Dou and Shanshan Zhu. Synthesis of highly fluorescent lysine-stabilized Au nanoclusters for sensitive and selective detection of Cu2+ ion. Journal of Materials Chemistry C, 2013, 1: 6748-6751. (SCI, IF=5.256)

24. Xiaoming Yang*, Yao Dou and Shanshan Zhu. Highly sensitive detection of superoxide dismutase based on an immunoassay with surface-enhanced fluorescence. Analyst, 2013, 138:3246-3252. (SCI, IF=3.885)

25. Yao Dou, Xiaoming Yang*. Novel high-sensitive fluorenscent detection of deoxyribonuclease I based on DNA-templated gold/silver nanoclusters. Analytica Chimica Acta, 2013, 784:53-58. (SCI, IF=4.950)

26. Yao Dou, Xiaoming Yang*, Zhongde Liu and Shanshan Zhu. Homocysteine-functionalized silver nanoparticles for selective sensing of Cu2+ ions and Lidocaine hydrochloride. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 423:20-26. (SCI, IF=2.714)

27. Xiaoming Yang*, Hongchang Li, Anping Deng and Xiaoqi Liu. Plk1 phosphorylation of topors is involved in its degradation. Molecular Biology Reports, 2010, 37:3023-3028. (SCI, IF=1.828)

28. Xiaoming Yang, Hongchang Li, Zinan Zhou, Wen-Hong Wang, Anping Deng, Ourania Andrisani and Xiaoqi Liu*. Plk1-mediated phosphorylation of topors regulates P53 stability. Journal of Biological Chemistry, 2009, 284:18558-18592. (SCI, IF=4.125)

29. Xiaoming Yang, Hongchang Li, Shawn Liu, Anping Deng and Xiaoqi Liu*. CDC2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication. Journal of Biological Chemistry, 2009, 284:28775-28782. (SCI, IF=4.125)

30. Zhao-Qiu Wu, Xiaoming Yang, Gregory Weber and Xiaoqi Liu*. PLK1 Phosphorylation of TRF1 is essential for its binding to telomers. Journal of Biological Chemistry, 2008, 283:25503-25513. (SCI, IF=4.125)

31. Jiabin Tang, Xiaoming Yang and Xiaoqi Liu*. Phophorylation of PLK1 at Ser-326 regulates its functions during mitotic progression. Oncogene, 2008, 27:6635-6645. (SCI, IF=7.519)

32. Hongchang Li, X Shawn Liu, Xiaoming Yang, Bing Song, Yun Wang and Xiaoqi Liu*. Polo-like kinase 1 Phosphorylation of p150Glued facilitates nuclear envelope breakdown during prophase. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107(33):14633-14638. (SCI, IF=9.661)

33. Hongchang Li, X Shawn Liu, Xiaoming Yang, Yingmin Wang, Yun Wang, Jerrold R Turner and Xiaoqi Liu*. Phosphorylation of CLIP-170 by PLK1 and CK2 promotes timely formation of kinetochore-microtubule attachments. the EMBO Journal, 2010, 29:2953-2965. (SCI, IF=9.792)