罗雷 博士 二级教授 博士生导师

西南大学药学院 院长

国家万人计划领军人才，国家重点研发计划青年首席，农业农村部新兽药咨询评审专家，重庆市学术技术带头人，西南大学“含弘领军岗”教授，西南大学学位评定委员会副主席，西南大学党委委员

学士、硕士、博士，分别毕业于中国药科大学、英国Loughborough University和University of Sheffield。

主持“十四五”国家重点研发计划青年科学家项目、重庆市杰出青年科学基金项目、国家自然科学基金和重庆市科技项目等科技开发项目30余项。研发的国内首个动物专用利胆药孟布酮（化药类），获国家二类新兽药证书3项，制定新兽药国家标准和残留检测标准4项，获准产品批文8项；获美国发明专利授权1项、中国发明专利授权5项；获人用药新药临床批件并参与多项新药注册发补；在药学期刊Nat. Comm., Adv. Sci., J. Control Release, Acta Pharm. Sin. B等发表论文30余篇；获教育部霍英东青年科学奖、重庆市首席专家工作室领衔专家、“2021十大重庆科技创新年度人物”称号，2022“强国青年科学家”提名人选、西南大学含弘光大学者奖。任《中国药业》副主编、Asian J. Pharm.编委、重庆市药学会副理事长、重庆市兽药工程技术中心主任、教育部药学类专业教指委委员，中国畜牧兽医学会兽医药理毒理学分会常务理事、中国药品监督管理研究会理事、重庆市药品监督管理局药械妆专家委员会委员、重庆市药学会药理、药剂专委会副主任委员、国家生猪技术创新中心特聘研究员、国家奶牛疾病防治科技创新联盟常务理事。

获重庆市教学成果二等奖，主编《兽医药理学实验教程》《药理学实验教程》，参编《药剂学》《工业药剂学》《生物药剂学》等教材。主讲《药剂学》、《工业药剂学》、《生物药剂学与药物动力学》等课程，全英文《药剂学》被重庆市教委评为重庆市来华留学英语授课品牌课程。指导学生获中国国际“联网+”大学生创新创业大赛重庆赛区选拔赛金奖。

团队研究方向：药物制剂、新药/新兽药和药用辅料的创制及产业化。

PUBLICATIONS （代表作）

1. Zhang, TL; Jin, P; Liu, MT; Sha, J; Gao, XQ; Feng, LQ; Yao, H; Liu, XW; Shao, H; Yu, YL; Fang, ZG; Luo, L. Glucosamine-triggered sustainable redox process for efficient degradation of tetracycline antibiotics. Chemical Engineering Journal. 2026 Feb1; 529:173062.

2. Yu, Y., Xu, Y., Yu, Z., Liu, X., Guo, J., Xiang, M., ... & L. Luo*. Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis[J]. Nature Communications, 2025 1329 .

3. Liu, M., Liu, X., Zhang, T., Wang, Y., Yao, H., Liu, X., ... & L. Luo*. Hypoxia-responsive hybrid nanoparticles loaded with fingolimod and colistin against multidrug-resistant Klebsiella pneumoniae with mature biofilm[J]. Asian Journal of Pharmaceutical Sciences, 2025: 101107.

4. Hussain, S., Dagah, O. M., Obaid, E. A., Jin, P., Dar, O. A., Irfan, M., ... & L. Luo*. Chitosan as oral absorption enhancer and inhibitor: A comprehensive review[J]. Chinese Chemical Letters, 2025: 111273.  

5. Zhang, T., Gao, X., Liu, M., Wen, C., Jin, P., Yao, H., ... & L. Luo*. Ambroxol hydrochloride as an antibiofilm agent synergizes with tetracycline antibiotics against mature biofilms of multidrug-resistant Klebsiella pneumoniae[J]. Biofilm, 2025: 100315. 

6. Wu, Q., Wang, Q., Luo, X., Jin, P., Jin, M., Hussain, S., ... & L. Luo*. Glucosamine activates intestinal P-glycoprotein inhibiting drug absorption[J]. Nature Communications, 2025, 16(1): 6100. 

7. Yu, Y., Liao, Z., Luo, X., Zhang, T., Yu, Z., Liu, X., ... & L. Luo*. A porridge-like hydrogel promoted the oral bioavailability of veterinary medicines[J]. International Journal of Pharmaceutics, 2025: 125648. 

8. Yu, Y., Hussain, S., Qi, J., L. Luo*, & Zhang, X. Mechanisms and applications: Cargos transport to basolateral membranes in polarized epithelial cells[J]. Chinese Chemical Letters, 2024, 35(12): 109673. 

9. Y. Yu*, S. Zhang, Y. Xu, H. Shao,L. Luo*. Oral delivery of ferroptosis inducers for effective treatment of hepatic fibrosis[J]. Nano Research, 2024, 17 7621–7630. 

10. Y. Yu, X. Tang, L. Zhou, F. Xu, Y. Zhang, L. Zeng, J. Li, G. Liao*, L. Luo*.Cascade-targeting polymeric particles eliminate intracellular C. neoformans in fungal infection therapy[J]. Journal of Controlled Release, 2024, 373 399–409. 

11. Y. Qi, M. Jin, Q. Li, Q. Wu, Z. Liao, M. Wei, X. Fan, Q. Yang, X. Tian, B. Giuseppe, L. Luo*. Chitooligosaccharide reconstitutes intestinal mucus layer to improve oral absorption of water-soluble drugs[J]. Journal of Controlled Release, 2023, 360 831–841.

12. Q. Ren, X. Tang, Y. Lu, Q. Li, Z. Liao, S. Jiang, H. Zhang, Z. Xu, L. Luo*. Design, Preparation and Pharmacodynamics of ICG-Fe(Ⅲ) Based HCPT Nanocrystals Against Cancer [J]. Asian Journal of Pharmaceutical Sciences, 2022, 17(4):596-609.

13. L. Luo, Yiming Qi, Hong Zhong, Shinan Jiang, Hu Zhang, Hao Cai, Yahui Wu, Zhongwei Gu, Qiyong Gong, Kui Luo,*. GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine [J]. Acta Pharmaceutica Sinica B, 2022;12(1):424-436.

14. Q. Wu, Y. Chen, Q. Li, J. Chen, J. Mo, M. Jin, Q. Yang, L. Rizzello, X. Tian, and L. Luo*. Time Rules the Efficacy of Immune Checkpoint Inhibitors in Photodynamic Therapy [J]. Advanced Science, 2022, 2200999.

15. L. Luo, Z. Yin, Y.M. Qi, S. LIU, Y. YI, X.H. TIAN, Y.H. WU, D. ZHONG, Z.W. GU, H. ZHANG, K LUO∗. An intracellular enzyme-responsive polymeric prodrug with synergistic effect of chemotherapy and two-photon photodynamic therapy [J]. Applied Materials Today, 2021, 23: 100996.

16. L. Luo*, F.S. Xu, H.L. Peng, Y.H. LUO, X.H. TIAN, G. Battaglia, H. ZHANG, Q.Y. GONG, Z.W. GU, K. LUO*. Stimuli-responsive polymeric prodrug-based nanomedicine delivering nifuroxazide and doxorubicin against primary breast cancer and pulmonary metastasis[J]. Journal of Controlled Release, 2020, 318: 124-135.

17. J.B. Liu, X. Yuan, L.D. Deng, Z. YIN, X.H. TIAN, S. Bhattacharyya, H.R. LIU, Y.H. LUO, L. LUO*. Graphene Oxide activated by 980 nm Laser for Cascading Two-Photon Photodynamic Therapy and Photothermal Therapy Against Breast Cancer[J]. Applied Materials Today, 2020, 20: 100665.

18. L. Luo*, Q. Zhang, Y.H. Luo, Z.G. HE, X.H. TIAN, G. Battaglia*. Thermosensitive nanocomposite gel for intra-tumoral two-photon photodynamic therapy[J]. Journal of Controlled Release, 2019, 298: 99-109.