付爱玲,教授,博士生导师,教育部新世纪优秀人才。
1、教育工作经历
1990.09-1993.07,河南大学,药学院
1996.09-2002.07,沈阳药科大学,硕士/第三军医大学,讲师
2002.08-2007.07,军事医学科学院,博士/复旦大学,博士后
2009.09-2010.10,美国加州大学洛杉矶分校,医学院,访问学者
2013.11-2014.11,美国麻省大学阿默斯特分校,化学系,访问学者
2007.07-至今,西南大学,药学院,教授
2、研究方向及成果
主要承担药学院本科生的生物化学、研究生的高级药理学和高级分子生物学教学。先后主持国家自然科学基金、教育部博士点基金、重庆市自然科学基金等多个科研项目。科研方向主要为药物靶脑递送(brain-targeting drug delivery)和线粒体治疗(mitotherapy)。分别在Frontier in Pharmacology, Neuropharmacology, Drug Delivery等国内外学术期刊上发表论文80余篇,其中SCI论文40多篇。出版著作2部,教材2部,授权专利3项,研究成果脑内重大疾病的治疗方法与机制研究获得重庆市自然科学奖一项。
近3年发表的主要论文如下:
1)Wang H, Chen L, Sun X, Fu A*. Intracellular localization of proteins to specific cellular areas by nanocapsule mediated delivery. J Drug Target. 2017, 25(8):724-733.
2)Fu A*, Shi XS, Zhang HQ, Fu B. Mitotherapy for fatty liver by intravenous administration of exogenous mitochondria in male mice. Frontiers in Pharmacology. 2017, 5, 1-8.
3) Shi XS, Zhao M, Fu C, Fu A*. Intravenous administration of mitochondria for treating experimental Parkinson’s disease. Mitochondrion. 2017, 34, 91-100.
4) Fu C, Qian K, Fu A*. Arginine-modified carbon dots probe for live cell imaging and sensing by increasing cellular uptake efficiency. Mater Sci Eng C. 2017, 76(1): 350-355.
5)Chen L, Fu C, Deng Y, Wu W, Fu A*. A pH-Sensitive Nanocarrier for Tumor Targeting: Delivery of Ruthenium Complex for Tumor Theranostic by pH-Sensitive Nanocapsule. Pharm Res. 2016; 33(12):2989-2998.
6) Wu J, Zhang E, Fu A*. A novel cell-permeable RDP-p53 fusion protein for specific inhibition on the growth of cancerous neural cells. Drug Delivery. 2016; 23(7):2464-2470.
7) Zhang E, Fu A*. A new strategy for specific imaging of neural cells based on peptide-conjugated gold nanoclusters. Int J Nanomedicine. 2015, 10: 2115-2124.
8) Qian K, Wu J, Zhang E, Zhang Y, Fu A*. Biodegradable double nanocapsule as a novel multi-functional carrier for drug delivery and cell imaging. Int J Nanomedicine. 2015,10: 4149-4157.
9) Fu A, Tang R, Hardie J, Farkas ME, Rotello VM. Promises and pitfalls of intracellular delivery of proteins. Bioconjug Chem. 2014, 25(9):1602-1608.