药物分析学教授、博士、博士生导师

  国家杰出青年基金获得者、新世纪百千万人才工程国家级人选、重庆“**学者”特聘教授；重庆市英才计划·优秀科学家

    联系方式

   E-mail: chengzhi@swu.edu.cn

 个人简介

 北京大学博士、北京师范大学硕士、西南师范大学学士、日本日立制作所中央研究所客员研究员、加拿大渥太华大学和日本东京大学博士后。主持国家杰出青年科学基金、国家自然科学基金重点及面上项目、科技部重大科学研究计划子课题、国家重点基础研究发展计划（973计划）课题等国家、省、部级项目20多项；研究成果获教育部和重庆市自然科学一等奖各1项，重庆市自然科学三等奖2项；主编学术专著1部，教材2本；授权发明专利10多项；在Angew. Chem. Int. Ed.、Biomaterials、Adv. Funct. Mater.、ACS Nano、Anal. Chem.、Chem. Sci.等国内外学术期刊上发表学术论文500多篇，引用16000余次。

研究方向简介

 药物光谱分析：包括生物计算、智能药物分析、能量转移光谱分析、纳米组装体与生物成像、病毒侵染细胞实时分析。即，通过设计并制备功能化荧光碳点、DNA纳米组装体等新型光谱探针，利用其优异的电化学发光、化学发光、荧光等性质，建立复杂介质中药物的实时在线和智能检测分析法、开发新的光学检测技术和药品质量控制技术。

代表性专著、教材

      1. 黄承志、凌剑、王健等编著. 弹性光散射光谱分析. 北京: 科学出版社, 2017.

      2. 黄承志、范琦、陈子林等编. 基础分析化学. 北京: 科学出版社, 2016.

3. 黄承志、范琦、陈子林等编. 基础仪器分析. 北京: 科学出版社, 2017.

代表论文

1. Yang, F. F.; Li, C. H.; Lv, W. Y.; Zhen, S. J. *; Huang, C. Z. * Deoxyribonucleic Acid Photonic Wires with Three Primary Color Emissions for Information Encryption. Adv. Funct. Mater. 2021: 2100322.

2. Pan, Z. Y.; Gao, P. F.; Jing, C. J.; Zhou, J.; Liang, W. T.; Lei, G.; Feng, W.; Li, Y. F.*; Huang, C. Z*. Microscopic electron counting during plasmon-driven photocatalytic proton coupled electron transfer on a single silver nanoparticle. Appl. Catal. B Environ. 2021, 291: 120090.

3. Lv, W. Y.; Li, C. H.; Li, Y. F.; Zhen, S. J. *; Huang, C. Z. * Hierarchical Hybridization Chain Reaction for Amplified Signal Output and Cascade DNA Logic Circuits. Anal. Chem. 2021, 93, 3411-3417.

4. Li, C. H.; Lv, W. Y.; Yan, Y.; Yang, F. F.; Zhen, S. J. *; Huang, C. Z*. Nucleolin-Targeted DNA Nanotube for Precise Cancer Therapy through Förster Resonance Energy Transfer-Indicated Telomerase Responsiveness. Anal. Chem. 2021, 93, 3526-3534.

5. Jiang, Z. W.; Zou, Y. C.; Zhao, T. T.; Zhen, S. J.; Li, Y. F. *; Huang, C. Z. * Controllable Synthesis of Porphyrin-Based 2D Lanthanide Metal-Organic Frameworks with Thickness- and Metal-Node-Dependent Photocatalytic Performance. Angew. Chem.-Int. Edit. 2020, 59, 3300-3306.

6. Jiang, Y. J.; Wang, N.; Cheng, F.; Lin, H. R.; Zhen, S. J.; Li, Y. F.; Li, C. M.*; Huang, C. Z.*, Dual energy transfer-based DNA/graphene oxide nanocomplex probe for highly robust and accurate monitoring of apoptosis-related micrornas. Anal. Chem., 2020, 92, 11565-11572.

7. Yan, X.; Xia, C.; Chen, B.; Li, Y. F.; Gao, P. F.*; Huang, C. Z.* Enzyme Activity Triggered Blocking of Plasmon Resonance Energy Transfer for Highly Selective Detection of Acid Phosphatase. Anal. Chem. 2020, 92, 2130-2135.

8. Wang, J. R.; Xia, C.; Yang, L.; Li, Y. F.; Li, C. M. *; Huang, C. Z.*, DNA Nanofirecrackers Assembled through Hybridization Chain Reaction for Ultrasensitive SERS Immunoassay of Prostate Specific Antigen. Anal. Chem. 2020, 92, 4046-4052.

9. Yang, T.*; Zhan, L.; Huang, C. Z.*, Recent insights into functionalized electrospun nanofibrous films for chemo-/bio-sensors. TrAC-Trend. Anal. Chem. 2020, 124, 115813)

10. Chen, B. B.; Liu, M. L.; Huang, C. Z. * Carbon dot-based composites for catalytic applications. Green Chem. 2020, 22, 4034-4054.

11. Liu, J. H.; Li, D. Y.; He, J. H.; Yuan, D.; Li, R. S.; Zhen, S. J. *; Li, Y. F.; Huang, C. Z.*Polarity-Sensitive Polymer Carbon Dots Prepared at Room-Temperature for Monitoring the Cell Polarity Dynamics during Autophagy. ACS Appl. Mater. Interfaces 2020, 12, 4815-4820.

12. Cheng, Y. Y.; Xie, Y. F.; Li, C. M.*; Li, Y. F.; Huang, C. Z.*, Förster resonance energy transfer-based soft nanoballs for specific and amplified detection of microRNAs. Anal. Chem. 2019, 91, 11023-11029.

13. Liu, M. L.; Chen, B. B.; Li, C. M.; Huang, C. Z.* Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications. Green Chem. 2019, 21, 449-471.

14. Chai, S. Q.; Lv, W. Y.; He, J. H.; Li, C. H.; Li, Y. F.; Li, C. M.*; Huang, C. Z.*, Dual energy transfer-based fluorescent nanoprobe for imaging miR-21 in nonalcoholic fatty liver cells with low background. Anal. Chem. 2019, 91 (10), 6761-6768.

15. Cheng, Y. Y.; Li, C. M.*; Mu, R. Z.; Li, Y. F.; Xing, T. T.; Chen, B. B.; Huang, C. Z.*, Dynamically long-term imaging of cellular RNA by fluorescent carbon dots with surface isoquinoline moieties and amines. Anal. Chem. 2018, 90 , 11358-11365.

16. Liu, J. H.; Li, R. S.; Yuan, B.; Wang, J. *; Li, Y. F.; Huang, C. Z.* Mitochondria-targeting single-layered graphene quantum dots with dual recognition sites for ATP imaging in living cells. Nanoscale 2018, 10, 17402-17408.

17. Lei, G.; Gao, P. F. *; Yang, T.; Zhou, J.; Zhang, H. Z.; Sun, S. S.; Gao, M. X.; Huang, C. Z*. Photoinduced Electron Transfer Process Visualized on Single Silver Nanoparticles. ACS Nano 2017, 11, 2085-2093.

18. Li, R. S.; Gao, P. F.; Zhang, H. Z.; Zheng, L. L.; Li, C. M.; Wang, J.; Li, Y. F.; Liu, F.; Li, N. *; Huang, C. Z.* Chiral nanoprobes for targeting and long-term imaging of the Golgi apparatus. Chem. Sci. 2017, 8, 6829-6835. (IF= 9.346)

19. Li, C. M.; Zheng, L. L.; Yang, X. X.; Wan, X. Y.; Wu, W. B.; Zhen, S. J.; Li, Y. F.; Luo, L. F.; Huang, C. Z.* DNA-AuNP networks on cell membranes as a protective barrier to inhibit viral attachment, entry and budding. Biomaterials, 2016, 77, 216-226.

20. Gao, P. F.; Gao, M. X.; Zou, H. Y.; Li, R. S.; Zhou, J.; Ma, J.; Wang, Q.; Liu,F.; Li, N.;* Li, Y. F.; Huang, C. Z.* Plasmon-Induced Light Concentration Enhanced Imaging Visibility as Observed by a Composite-Field Microscopy Imaging System. Chem. Sci. 2016, 7, 5477-5483.