刘慧 副教授（硕导）

教育及工作经历：

2005/07-至今 西南大学 药学院， 教师

2014/12-2015/12 美国纽约州立大学布法罗分校生化工程系 博士后

2009/09-2013/12 西南大学，分析化学，博士

教学：主要承担本科生《药物分析》与《药物分析实验》课程教学。主持制作虚拟实验软件一项；主持教改项目两项;发表教改论文一篇；2017年参加教育部高等学校药学专业教学指导委员会主办的青年教师教学能力大赛，并获一等奖。

科研：研究方向为生化药物分析，主要进行发光材料制备及其在药物分析和疾病诊断中的应用研究。

主持科研项目：

• 国家自然科学基金（青年基金项目），多色碳点的可控合成及其在肿瘤标志物联合检测中的应用 （No. 21705131），24万，2018/01/01-2020/12/31

• 重庆市自然科学基金面上项目联合资助，深度学习用于碳点智能化合成及肿瘤细胞识别（CSTB2022NSCQ-MSX1519），10万，2022/08/1-2025/07/31

• 西南大学博士基金，基于荧光共振能量转移将荧光碳点用于疾病相关的生化分析（No. SWU114020），5万，2014/06-2016/12

• 中央高校基本业务费一般项目，功能化石墨烯在癌症治疗药物靶向传递中的应用研究 （No. XDJK2010C066），5万，2010/11-2012/12

论文：

• Jiao Chen, Jun Bo Luo, Mu Yuan Hu, Jun Zhou, Cheng Zhi Huang*, Hui Liu*. Controlled Synthesis of Multicolor Carbon Dots Assisted by Machine Learning. Advanced Functional Materials, 2022, 22, 2210095  

• Jia Hui He, Yun Ying Cheng, Qian Qian Zhang, Hui Liu*, Cheng Zhi Huang*. Carbon dots-based fluorescence resonance energy transfer for the prostate specific antigen (PSA) with high sensitivity. Talanta, 2020, 219, 121276.

• Hui Liu, Yue Zhang, Cheng Zhi Huang*. Development of nitrogen and sulfur-doped carbon dots for cellular imaging. Journal of Pharmaceutical Analysis, 2019, 9(2), 127-132

• Meng Li Liu, Lin Yang, Rong Sheng Li, Bin Bin Chen, Hui Liu*, Cheng Zhi Huang*. Large-scale simultaneous synthesis of highly photoluminescent green amorphous carbon nanodots and yellow crystalline graphene quantum dots at room temperature. Green Chemistry, 2017, 19, 3611-3617

• Hui Liu, Rong Sheng Li, Jun Zhou, Cheng Zhi Huang*. Branched polyethylenimine-functionalized carbon dots as sensitive and selective fluorescent probes for N-acetylcysteine via an off-on mechanism. Analyst, 2017, 142, 4221-4227，

• Hui Liu, Yue Zhang, Jia Hui Liu, Peng Hou, Jun Zhou, Cheng Zhi Huang*. Preparation of nitrogen-doped carbon dots with high quantum yield from Bombyx mori silk for Fe(III) ions detection. RSC Advance, 2017,7, 50584-50590

• 刘慧, 刘梦丽, 侯鹏, 黄承志*. 异元素掺杂碳点的制备及其在生物成像中的应用. 分析化学. 2017, 45, 1845-1856

• 刘慧，黄承志*.荧光碳点与小檗碱类药物的作用及盐酸药根碱的选择性测定. 中国科学：化学. 2016, 46, 810-815

• Ping Ping Hu, Hui Liu, Shu Jun Zhen, Chun Mei Li, Cheng Zhi Huang* Nanosilver-based surface-enhanced Raman spectroscopic determination of DNA methyltransferase activity through real-time hybridization chain reaction. Biosensors and Bioelectronics. 2015, 73, 228-233. （共同一作）

• Yun Huan Yuan, Ze Xi Liu, Rong Sheng Li, Hong Yan Zou, Min Lin, Hui Liu*, Cheng Zhi Huang*. Synthesis of nitrogen-doping carbon dots with different photoluminescent properties by controlling the surface states. Nanoscale, 2016, 12, 6770-6776

• Ze Xi Liu, Zhu Lian Wu, Ming Xuan Gao, Hui Liu*, Cheng Zhi Huang*. Carbon dots with aggregation induced emission enhancement for visual permittivity detection. Chemical Communications, 2016, 52, 2063-2066

• Min Lin, Hong Yan Zou, Tong Yang, Ze, Xi Liu, Hui Liu*, Cheng Zhi Huang*. An inner filter effect based sensor of tetracycline hydrochloride as developed by loading photoluminescent carbon nanodots in the electrospun nanofibers. Nanoscale, 2016, 8, 2999-3007

• Yun Huan Yuan, RongSheng Li, Qiang Wang, Zhu lian Wu, Jian Wang, Hui Liu*, Cheng Zhi Huang*. Germanium-doped carbon dots as a new type of sensitive and selective fluorescent probe for visualizing the dynamic invasions of mercury (II) ions into cancer cells. Nanoscale, 2015, 7, 16841-16847.

• Gang Lei, Peng Fei Gao, Hui Liu*, Cheng Zhi Huang*. Real-time scattered light dark-field microscopic imaging of the dynamic degradation process of sodium dimethyldithiocarbamate. Nanoscale, 2015, 7, 20709-20716.

电子邮箱：liuhui78@swu.edu.cn