基本信息
田东松,副教授,德国莱布尼兹汉诺威大学微生物化学博士(极优等Magna Cum Laude)。研究方向为药物活性分子的生物合成及化学酶法合成,主持国家自然科学基金、重庆市自然科学基金、重庆市留学人员回国项目、中央高校基本科研业务费项目,并在Natural Product Reports、Chemical Science、Organic Letters、Bioresource Technology等领域代表期刊发表研究论文。承担本科生/留学生/硕博研究生《有机化学》、《药物合成反应》、《Pharmaceutical Chemistry》、《现代药学研究与开发》、《生物医药产业创新》等课程教学。
个人经历
2022.12 至今:西南大学药学院讲师、副教授
2021-2022:德国莱布尼兹汉诺威大学,生物活性分子药物研究中心,研究助理
2017-2021:德国莱布尼兹汉诺威大学,博士(导师:Prof. Russell J. Cox,FRSC)
2014-2017:贵州大学药学院,硕士(导师:郝小江院士、苑春茂研究员)
代表论著
8. Chunxia Xiao, Mengfei Long, Xiaoxue Sun, Dashun Yi, Md Sharuf Miah, Siyi Yang, Hang Ma, Dongsong Tian*, Russell J. Cox, Xiao Zhang*, Baoshun Zhang*. Characterization and employment of novel α-ketoglutarate dependent oxygenases for efficient synthesis of antifungal alkyl citrates. Bioresource Technology, 2026, 443, 133787
7. Dongsong Tian, Xiao Zhang* and Russell J. Cox*. Comparing the Efficiency of Total Chemical Synthesis and Total Biosynthesis of Fungal Specialized Metabolites. Natural Product Reports, 2025, 42, 720-738
6. Yunlong Sun#, Dongsong Tian#, Eric Kuhnert, Geraldine Le Gof, Guillaume Arcile, Jamal Ouazzani, Russell J. Cox*. Total biosynthesis of fungal tetraketide pyrones, Chemical Communications, 2023, 59(91), 13587–13590(共同一作)
5. Dongsong Tian. Biosynthesis of sporothriolides and sporochartines in fungi. Gottfried Wilhelm Leibniz Universität, 2021
4. Dong-Song Tian, Eric Kuhnert, Jamal Ouazzani, Daniel Wibberg, Jorn Kalinowski, and Russell J. Cox*. The sporothriolides. A new biosynthetic family of fungal secondary metabolites. Chemical Science, 2020, 11(46), 12477–12484
3. Xin Lin#, Dongsong Tian#, Yanhui Fu, Yanan Li, Liejun Huang, Wei Gu, Jialei Song, Yanmei Li, Yaacov Ben-David, Min Wen*, Chunmao Yuan*, Xiaojiang Hao*. Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase. European Journal of Medicinal Chemistry, 2019, 162, 765–780(共同一作)
2. Dong-Song Tian, Wei Gu, Lie-Jun Huang, Tao Huang, Yi-Min Fan, Yan-Hui Fu, Jian-Xin Zhang, Chun-Mao Yuan*, Xiao-Jiang Hao*. Cytotoxic and anti-oxidant biphenyl derivatives from the leaves and twigs of Garcinia multiflora. Phytochemistry Letters, 2017, 19, 132–135
1. Dong Song Tian#, Ping Yi#, Lei Xia, Xin Xiao, Yi Min Fan, Wei Gu, Lie Jun Huang, Yaacov Ben-David, Ying Tong Di, Chun Mao Yuan*, and Xiao Jiang Hao*. Garmultins A–G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora. Organic Letters, 2016, 18(22), 5904–5907
联系方式
dstian@swu.edu.cn
欢迎具有微生物学、分子生物学、天然药物化学基础,有志于生物合成、酶催化、酶学机制研究的研究生/本科生联系
Welcome the students who are interested in biosynthesis and enzyme catalytic mechanisms.