
个人信息:
张华然,博士,西南大学讲师,籍贯四川绵阳
研究方向:
(1)真菌活性次级代谢产物生物合成与酶学机制
(2)真菌新颖次级代谢产物基因组挖掘
教育及工作经历:
2022.7-至今 |
西南大学 |
药学院 |
讲师 |
2019.9-2022.6 |
中国科学院大学 |
南海海洋研究所 |
博士 |
2016.9-2019.6 |
山东大学 |
药学院 |
硕士 |
2011.9-2015.6 |
中国药科大学 |
中药学院 |
学士 |
代表性文章:
1. Zhang, H.; Gong, N.; Zhang, H.; Li, Q.; Ma, J. Wei, X.; Li, W; Ju, J, Characterization of the glycosyltransferase and methyltransferase encoded remotely from the actinopyrone biosynthetic gene cluster enables access to diverse analogues. Organic Letters 2022, 24 (49), 9065–9070.
2. Zhang, H.; Zhang, C.; Li, Q.; Ma, J.; Ju, J., Metabolic blockade-based genome mining reveals lipochain-linked dihydro-β-alanine synthetases involved in autucedine biosynthesis. Organic Letters 2022, 24 (30), 5535-5540.
3. Zhang, H.; Zhang, X.; Huang, Y.; Yuan, J.; Wei, X.; Ju, J., Discovery, structure correction, and biosynthesis of actinopyrones, cytotoxic polyketides from the deep-sea hydrothermal-vent-derived Streptomyces sp. SCSIO ZS0520. Journal of Natural Products 2022, 85 (3), 625-633.
4. Zhang, H.; Chen, Y.; Li, Y.; Song, Y.; Ma, J.; Ju, J., Secondary metabolites and biosynthetic gene clusters analysis of deep-sea hydrothermal vent-derived Streptomyces sp. SCSIO ZS0520. Marine Drugs 2022, 20 (6), 393.
5. Zhang, H.; Xu, L.; Liu, X.; Fan, J.; Wang, X.; Shen, T.; Wang, S.; Ren, D., Dracomolphesin A–E, five 3,4-seco-phenylpropanoids with Nrf2 inducing activity from Dracocephalum moldavica. Chinese Chemical Letters 2020, 31 (5), 1259-1262.
联系方式:
邮箱:aifyui@126.com
通信地址:重庆市北碚区西南大学药学院505