个人信息
田东松，1990年生，中共党员（2010），籍贯河南灵宝。2011年毕业于中国药科大学，2014年至2017年于贵州大学攻读药物化学硕士学位，师从中国科学院院士郝小江研究员。2017年至2021年获国家留学基金委资助，赴德国莱布尼兹汉诺威大学攻读微生物化学博士学位，Mentor是Russell J. Cox教授。2021年12月开始在德国莱布尼兹汉诺威大学生物活性分子药物研究中心做研究助理-博士后研究员。2022年12月加入西南大学药学院，研究方向是真菌次级代谢产物的生物合成及合成生物学。目前以第一作者在Chemical Science、Organic Letters、Chemical Communications、European Journal of Medicinal Chemistry等杂志发表研究论文数篇。目前承担本科生《药物合成反应》、《有机化学》，留学生班《Organic Chemistry》等课程教学任务。
研究方向与兴趣
真菌次级代谢产物的生物合成机制及合成生物学
联系方式
dstian@swu.edu.cn
学习经历
2008.9-2011.6：中国药科大学，化学制药技术
2014.9-2017.6：贵州大学，药物化学，理学硕士，导师：郝小江院士
中国科学院昆明植物研究所（2016）
贵州省中科院天然产物化学重点实验室（2015-2017）
2017.9-2021.9：德国汉诺威大学 Gottfried Wilhelm Leibniz Universität Hannover，微生物化学博士，Mentor: Prof. Russell J. Cox
2021.12-2022.12：Gottfried Wilhelm Leibniz Universität Hannover, Centre of Biomolecular Drug Research, Postdoctoral Researcher, Mentor: Prof. Russell J. Cox
工作经历
2022.12-至今：西南大学药学院讲师，研究团队：张霄教授课题组
2011.8-2013.4：南京丰融化学技术有限公司，药物合成助理
2011.1-2011.4：南京绿叶思科药业有限公司，紫杉醇脂质体制剂车间实习生
获奖
2011 优秀毕业生，中国药科大学
2017 优秀研究生毕业论文，贵州大学
2017 国家建设高水平大学公派博士奖学金，国家留学基金委员会
2021 极优等博士毕业生荣誉 Magna Cum Laude, Gottfried Wilhelm Leibniz Universität Hannover
2021 优秀研究学者，2021法国、德国地区国家公派学者研讨会Online CSC-Seminar in Germany and France, Nordrhein-Westfalen, Germany
2021 研究生最佳汇报奖 BEST PRESENTATION AWARD FOR POSTGRADUATES, The 1st International Symposium on Marine Science and Engineering for Young Scientists and Postgraduates, Hong Kong
指导学生毕业课题
2022 Christina Panayi, M.Sc. Molekulare Mikrobiologie (Unfunctionalized pyrichalasin H skeleton), Leibniz Universität Hannover, Germany
2022 Stella Alandea, B. Sc. Chemie (Chemical Analysis of Genetically Modified Fungi), Leibniz Universität Hannover, Germany
发表论文
1. Dongsong Tian*, Russell J. Cox*, Xiao Zhang. Comparing the Efficiency of Total Chemical Synthesis and Total Biosynthesis of Fungal Specialized Metabolites. Natural Product Reports, 2024. (Invited, submitting)
2. Yunlong Sun#, Dongsong Tian#, Eric Kuhnert, Geraldine Le Gof, Guillaume Arcile, Jamal Ouazzani, Russell J. Cox*. Total biosynthesis of fungal tetraketide pyrones, Chemical Communications, 2023, 59(91), 13587–13590
3. Dongsong Tian. Biosynthesis of sporothriolides and sporochartines in fungi. Gottfried Wilhelm Leibniz Universität, 2021
4. Dong-Song Tian, Eric Kuhnert, Jamal Ouazzani, Daniel Wibberg, Jorn Kalinowski, and Russell J. Cox*. The sporothriolides. A new biosynthetic family of fungal secondary metabolites. Chemical Science, 2020, 11(46), 12477–12484
5. Haojie Yang, Dongsong Tian, Yanrong Zeng, Liejun Huang, Wei Gu, Xiaojiang Hao, Chunmao Yuan*. Biochemical Systematics and Ecology, 2020, 88, 103981
6. Zhuolun Li, Lihua Zuo, Yingying Shi, Dongsong Tian, Liwei Liu, Yantao Yang, Lin Zhou, Xiaojian Zhang, Jian Kang, Xiaojiang Hao, Chunmao Yuan*, Zhi Sun*. Journal of Separation Science, 2020, 43, 978-986
7. Xin Lin#, Dongsong Tian#, Yanhui Fu, Yanan Li, Liejun Huang, Wei Gu, Jialei Song, Yanmei Li, Yaacov Ben-David, Min Wen*, Chunmao Yuan*, Xiaojiang Hao*. Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase. European Journal of Medicinal Chemistry, 2019, 162, 765–780
8. Yan-Rong Zeng, Ping Yi, Wei Gu, Chun-Xia Xiao, Lie-Jun Huang, Dong-Song Tian, Hui Yan, Duo-Zhi Chen, Chun-Mao Yuan* and Xiao-Jiang Hao*. Organic & Biomolecular Chemistry, 2018, 16, 4195-4198
9. Dong-Song Tian, Wei Gu, Lie-Jun Huang, Tao Huang, Yi-Min Fan, Yan-Hui Fu, Jian-Xin Zhang, Chun-Mao Yuan*, Xiao-Jiang Hao*. Cytotoxic and anti-oxidant biphenyl derivatives from the leaves and twigs of Garcinia multiflora. Phytochemistry Letters, 2017, 19, 132–135
10. Dong Song Tian#, Ping Yi#, Lei Xia, Xin Xiao, Yi Min Fan, Wei Gu, Lie Jun Huang, Yaacov Ben-David, Ying Tong Di, Chun Mao Yuan*, and Xiao Jiang Hao*. Garmultins A–G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora. Organic Letters, 2016, 18(22), 5904–5907
国际国内会议汇报
1. 全国真菌生命与健康前沿交叉学术研讨会，重庆北碚，2023.11.10-2023.11.13，口头汇报
2. 2021 Online CSC-Seminar in Germany and France, Nordrhein-Westfalen, Germany, August 28th 2021. (Oral presentation)
3. The 1st International Symposium on Marine Science and Engineering for Young Scientists and Postgraduates, Hong Kong, July 12th – July 14th 2021. (Oral presentation, BEST PRESENTATION AWARD FOR POSTGRADUATES)
4. The Chemistry and Biology of Natural Products Symposium XIV, Warwick, United Kingdom, June 10th – June 11th 2021. (Oral presentation)
5. MegaSyn Symposium on Megasynthases 2020, Bad Nauheim near Frankfurt, Germany, September 29th – October 1st 2020. (Poster presentation and abstract oral presentation)
