Cheng Zhi HUANG
Ph. D and Professor
College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China
E-mail: chengzhi@swu.edu.cn
Tel: 86-23-68254659
Fax: 86-23-68367257
Education
1993.09-1996.07, Peking University, Analytical Chemistry (Ph.D )
1990.09-1993.07, Beijing Normal University, Analytical Chemistry (M.S.)
1982.09-1986.07, Southwest Normal University (B.S.)
Postdoctoral Fellow
2001.08-2003.07 |
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan. |
2000.12-2001.05 |
Department of Biochemistry, University of Ottawa, Canada. |
1998.11-1999.10 |
Central Research Laboratory of Hitachi, Ltd. (HCRL), Japan. |
Research Interest & Scientific Achievements
His main research field is resonance spectroscopy and spectral analysis and his main research interests include resonance light scattering spectral analysis, fluorescent spectral analysis, and resonance energy transfer spectral analysis. He has been undertaking two NSFC projects, including one key project and one general project. By now, he has presided over 30 projects of provincial and ministerial research projects, including the National Science Fund for Distinguished Young Scholars, National Program on Key Basic Research Project, and Key Program of National Natural Science Foundation of China. He has authored over 500 research articles in a number of authoritative journals such as Angew. Chem. Int. Ed., ACS Nano, Chem. Sci., Green Chem., Biomaterials, Anal. Chem., and Sci. Sin. Chim., etc. He has edited 1 book related to Elastic Light Scattering Spectrometry and 2 textbooks on Analytical Chemistry and Instrumental Analysis. He has also won several prizes and awards for his research. For example, the First Prize in Natural Science of Chongqing and the first prize of Natural Science by the Ministry of Education of China as the 2nd participant.
Selected Publications
1. Lv, W. Y.; Li, C. H.; Yang, F. F.; Li, Y. F.; Zhen, S. J.*; Huang, C. Z.* Sensitive logic and devices with strong response for weak inputs. Angew. Chem.-Int. Edit. 2022, 61, e202115561.
2. Yang, F. F.; Li, C. H.; Lv, W. Y.; Zhen, S. J.*; Huang, C. Z.* Deoxyribonucleic acid photonic wires with three primary color emissions for information encryption. Adv. Funct. Mater. 2021: 2100322.
3. Pan, Z. Y.; Gao, P. F.; Jing, C. J.; Zhou, J.; Liang, W. T.; Lei, G.; Feng, W.; Li, Y. F.*; Huang, C. Z.* Microscopic electron counting during plasmon-driven photocatalytic proton coupled electron transfer on a single silver nanoparticle. Appl. Catal. B Environ. 2021, 291: 120090.
4. Lv, W. Y.; Li, C. H.; Li, Y. F.; Zhen, S. J.*; Huang, C. Z.* Hierarchical hybridization chain reaction for amplified signal output and cascade DNA logic circuits. Anal. Chem. 2021, 93, 3411-3417.
5. Li, C. H.; Lv, W. Y.; Yan, Y.; Yang, F. F.; Zhen, S. J.*; Huang, C. Z*. Nucleolin-targeted DNA nanotube for precise cancer therapy through Förster resonance energy transfer-indicated telomerase responsiveness. Anal. Chem. 2021, 93, 3526-3534.
6. Jiang, Z. W.; Zou, Y. C.; Zhao, T. T.; Zhen, S. J.; Li, Y. F.*; Huang, C. Z.* Controllable synthesis of porphyrin-based 2D lanthanide metal-organic frameworks with thickness- and metal-node-dependent photocatalytic performance. Angew. Chem.-Int. Edit. 2020, 59, 3300-3306.
7. Jiang, Y. J.; Wang, N.; Cheng, F.; Lin, H. R.; Zhen, S. J.; Li, Y. F.; Li, C. M.*; Huang, C. Z.* Dual energy transfer-based DNA/graphene oxide nanocomplex probe for highly robust and accurate monitoring of apoptosis-related micrornas. Anal. Chem., 2020, 92, 11565-11572.
8. Yan, X.; Xia, C.; Chen, B.; Li, Y. F.; Gao, P. F.*; Huang, C. Z.* Enzyme activity triggered blocking of plasmon resonance energy transfer for highly selective detection of acid phosphatase. Anal. Chem. 2020, 92, 2130-2135.
9. Wang, J. R.; Xia, C.; Yang, L.; Li, Y. F.; Li, C. M.*; Huang, C. Z.* DNA nanofirecrackers assembled through hybridization chain reaction for ultrasensitive SERS immunoassay of prostate specific antigen. Anal. Chem. 2020, 92, 4046-4052.
10. Yang, T.*; Zhan, L.; Huang, C. Z.* Recent insights into functionalized electrospun nanofibrous films for chemo-/bio-sensors. TrAC-Trend. Anal. Chem. 2020, 124, 115813
11. Chen, B. B.; Liu, M. L.; Huang, C. Z.* Carbon dot-based composites for catalytic applications. Green Chem. 2020, 22, 4034-4054.
12. Liu, J. H.; Li, D. Y.; He, J. H.; Yuan, D.; Li, R. S.; Zhen, S. J. *; Li, Y. F.; Huang, C. Z.* Polarity-sensitive polymer carbon dots prepared at room-temperature for monitoring the cell polarity dynamics during autophagy. ACS Appl. Mater. Interfaces 2020, 12, 4815-4820.
13. Cheng, Y. Y.; Xie, Y. F.; Li, C. M.*; Li, Y. F.; Huang, C. Z.* Förster resonance energy transfer-based soft nanoballs for specific and amplified detection of microRNAs. Anal. Chem. 2019, 91, 11023-11029.
14. Liu, M. L.; Chen, B. B.; Li, C. M.; Huang, C. Z.* Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications. Green Chem. 2019, 21, 449-471.
15. Chai, S. Q.; Lv, W. Y.; He, J. H.; Li, C. H.; Li, Y. F.; Li, C. M.*; Huang, C. Z.* Dual energy transfer-based fluorescent nanoprobe for imaging miR-21 in nonalcoholic fatty liver cells with low background. Anal. Chem. 2019, 91(10), 6761-6768.
16. Cheng, Y. Y.; Li, C. M.*; Mu, R. Z.; Li, Y. F.; Xing, T. T.; Chen, B. B.; Huang, C. Z.* Dynamically long-term imaging of cellular RNA by fluorescent carbon dots with surface isoquinoline moieties and amines. Anal. Chem. 2018, 90, 11358-11365.
17. Liu, J. H.; Li, R. S.; Yuan, B.; Wang, J.*; Li, Y. F.; Huang, C. Z.* Mitochondria-targeting single-layered graphene quantum dots with dual recognition sites for ATP imaging in living cells. Nanoscale 2018, 10, 17402-17408.
18. Lei, G.; Gao, P. F. *; Yang, T.; Zhou, J.; Zhang, H. Z.; Sun, S. S.; Gao, M. X.; Huang, C. Z.* Photoinduced electron transfer process visualized on single silver nanoparticles. ACS Nano 2017, 11, 2085-2093.
19. Li, R. S.; Gao, P. F.; Zhang, H. Z.; Zheng, L. L.; Li, C. M.; Wang, J.; Li, Y. F.; Liu, F.; Li, N.*; Huang, C. Z.* Chiral nanoprobes for targeting and long-term imaging of the Golgi apparatus. Chem. Sci. 2017, 8, 6829-6835.
20. Li, C. M.; Zheng, L. L.; Yang, X. X.; Wan, X. Y.; Wu, W. B.; Zhen, S. J.; Li, Y. F.; Luo, L. F.; Huang, C. Z.* DNA-AuNP networks on cell membranes as a protective barrier to inhibit viral attachment, entry and budding. Biomaterials 2016, 77, 216-226.
21. Gao, P. F.; Gao, M. X.; Zou, H. Y.; Li, R. S.; Zhou, J.; Ma, J.; Wang, Q.; Liu,F.; Li, N.;* Li, Y. F.; Huang, C. Z.* Plasmon-induced light concentration enhanced imaging visibility as observed by a composite-field microscopy imaging system. Chem. Sci. 2016, 7, 5477-5483.
Professional Cultivation
Long-term recruitment of motivated young scientists, from graduate students to post-docs, from all over the world.
