张保顺 Baoshun Zhang

发布时间:2022-04-13 16:58:39 作者: 浏览次数: 次

Baoshun Zhang                   

Ph.D,  Professor. PhD supervisor.

Chongqing Commissioner of Science and Technology

College of Pharmaceutical Sciences

Southwest University, Chongqing, P.R. China 40016

Phone: 86-23-68251225; Fax: 86-23-68251048

Email: zbs360@swu.edu.cn

Dr. Zhang obtained his Ph.D in Medicinal Chemistry at College of Pharmaceutical Sciences from Southwest University (SWU) in 2011, and received his master and bachelor’s degrees in Natural Product Chemistry at SWU and Yangtze University, respectively. As a visiting scholar, he separately went to the University of Washington in 2012 and Illinois State University in 2018 to carry out the international research collaboration.

Dr. Zhang is a professor and engaged in the teaching and research of Medicinal chemistry, Pharmaceutical equipment and engineering design, and Physical chemistry. He is a commissioner of science and technology in Chongqing, and a vice director of Chongqing productivity promotion center for the modernization of TCM. Dr. Zhang as a principle investigator has obtained 30 project grants including the National Key Research and Development Program of China for TCM Modernization, NSFC-Youth Project, and the Chongqing Social Undertaking and Livelihood Security Project. He has applied 7 and awarded 3 invention patents (1 Australia international patent). Dr. Zhang has formulated 2 Chongqing standards and guidelines, and edited undergraduate textbook of Physical Chemistry. He has published more than 30 peer-reviewed research papers.

His research interests fouced primarily on: (1) Structure-based drug design (including Fragment-based approach, against inflammatory, cardiovascular and tumor diseases); Multivalent inhibitor design. (2) Pharmacological mechanism evaluation through the in vitro molecular and cell model, and the in vivo animal model with gene knock-out. Those potential mechanisms were revealed under relative signaling pathway. (3) Extract and purification of activated ingradients from natural plants, their pharmacological effects will screen in a high-throughput platform in our lab. Meanwhile, from the relation of structure-activity, the new compound can be redesign-based the former analysis of the binding form of the ligand and receptor.