Chen Min 
Ph. D and Professor
College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China
E-mail: mminchen@swu.edu.cn
Tel: 86-23-68250579
Fax: 86-23-68251225
Education:
2001-2004 Fudan University, Ph. D’s degree in Pharmacognosy
1998-2001 Southwest Normal University, Master’s degree in Botany
1994-1998 Southwest Normal University, Bachelor’s degree in Biology Education
Work Experience:
2016-Present Southwest University, College of pharmacy, vice dean. She is in charge of undergraduate education, National Demonstration Center for Experimental Pharmaceutical Education, as well as international cooperation and exchange.
2013-Present Southwest University, College of pharmacy, Professor
2011-2012 Department of Chemistry, University of British Columbia, Vancouver, Canada, Visiting professor
2006-2013 Southwest University, College of Pharmacy, Associate Professor
2004-2006 Southwest Normal University, College of Life Sciences, Associate Professor
Research Interest
Min Chen is a professor of Pharmacogonosy. The research interests of Dr. Chen's lab involve the discovery of active natural products from medicinal plants and their action mechanism, and the quality control of traditional Chinese medicine.
Grants and fundings
Natural Science Foundation of China (NSFC, 81102894, 81774005, 82074119).
National Key Technology R&D Program of China (Nos. 2010AA101603, 2011BAI13B06, 2011AA100607, 2010ZX09401-306-1-4).
Chongqing Science and Technology Projects (CSTC2006BB5343, cstc2017shmsA130079, 2021ZY013997).
Selected Publications: (Recent 5 years)
1. Fancheng Meng#, YingXiong Ma#, HongHong Zhan, Wei Zong, Lang Linghu, Zhe Wang, XiaoZhong Lan, ZhiHua Liao, and Min Chen*. Lignans from the seeds of Herpetospermum pedunculosum and their farnesoid X receptor-activating effect. Phytochemistry. 2022, 193, 113010.
2. Jingxin Mao#, Honghong Zhan#, Fancheng Meng, Guowei Wang, Dan Huang, Zhihua Liao, and Min Chen*. Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro. Phytotherapy Research. 2022, 36:1268–1283.
3. Xiaodong Wei, Yingxiong Ma, Zhaoyue Dong, Guowei Wang, Xiaozhong Lan, Zhihua Liao, and Min Chen*. Dehydrodiconiferyl alcohol, a lignan from Herpetospermum pedunculosum, alleviates cholestasis by activating pathways associated with the farnesoid X receptor. Phytomedicine. 2021. 80: 153378.
4. Rui Wang, Zhaoyue Dong, Fancheng Meng, Lin Wei, Guowei Wang, Siyu Zhou, Xiaozhong Lan, Zhihua Liao, and Min Chen *. Pterocephin A, a novel triterpenoid saponin from Pterocephalus hookeri induced liver injury by Activation of Necroptosis. Phytomedicine. 2021. 85, 153548.
5. Fancheng Meng, Wei Zong, XiaoDong Wei, YunYi Tao, Guowei Wang, ZhiHua Liao, and Min Chen *. Dolomiaea souliei ethyl acetate extract protected against α-naphthylisothiocyanate-induced acute intrahepatic cholestasis through regulation of farnesoid x receptor-mediated bile acid metabolism. Phytomedicine. 2021. 87，153588.
6. Zhaoyue Dong, Lin Wei, Huiqiang Lu, Qinghong Zeng a, Fancheng Meng, Guowei Wang, Xiaozhong Lan, Zhihua Liao, Min Chen *. Ptehoosines A and B: Two New Sesamin-type Sesquilignans with Antiangiogenic Activity from Pterocephalus hookeri (C.B. Clarke) Höeck. Fitoterapia. 2021. 151, 104886.
7. Xiaodong Wei, Xudong Fan, Zhiying Feng, Yingxiong Ma, Xiaozhong Lan, and Min Chen*. Ethyl acetate extract of Herpetospermum pedunculosum alleviates α-naphthylisothiocyanate-induced cholestasis by activating the farnesoid X receptor and suppressing oxidative stress and inflammation in rats. Phytomedicine. 2020, 76: 153257.
8. Zhaoyue Dong, Liqing Deng, Jingqiu Ge, Yingxiong Ma, Hong Quan, Xiaozhong Lan, Zhihua Liao, and Min Chen*. Pharmacokinetics and tissue distribution study of herpetotriol in rats by ultra-high performance liquid chromatography with tandem mass spectrometry. Canadian Journal of Physiology and Pharmacology, 2020, 98(6): 366-372.
9. Rui Wang, Zhaoyue Dong, Xiaozhong Lan, Zhihua Liao, and Min Chen*. Sweroside Alleviated LPS-Induced Inflammation via SIRT1 mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells. Molecules. 2019, 24, 872;
10. Rui Wang, Zhaoyue Dong, Xiaolong Zhang, Jingxin Mao, Fancheng Meng, Xiaozhong Lan, Zhihua Liao, Min Chen*. Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis. Toxins, 2019, 11, 142.
11. Liqing Deng, Wei Zong, Xueying Tao, Shuang Liu, Zhiying Feng, Yuping Lin, Zhihua Liao, and Min Chen*. Evaluation of the Therapeutic Effect against Benign Prostatic Hyperplasia and the Active Constituents from Epilobium angustifolium L. Journal of Ethnopharmacology. 2019, 232: 1-10.
12. Guowei Wang*, Xiaolong Zhang, Qinghua Wu, Yongbiao Jin, ChunTao Ning, Rui Wang, JingXin Mao, Min Chen*. The hepatoprotective effects of Sedum sarmentosum extract and its isolated major constituent through Nrf2 activation and NF-κB inhibition. Phytomedicine. 2019, 53: 263-273.
13. Yingxiong Ma, Hong Wang, Rui Wang, Fancheng Meng, Zhaoyue Dong, Guowei Wang, Xiaozhong Lan, Hong Quan* Zhihua Liao and Min Chen*. Cytotoxic lignans from the stems of Herpetospermum pedunculosum. Phytochemistry. 2019, 164:102-110.
14. SiYu Zhou; YiJie Hu; FanCheng Meng; ShenYue Qu; Rui Wang; Andersen Raymond J; ZhiHua Liao; Min Chen*. Bacillamidins A⁻G from a Marine-Derived Bacillus pumilus. Marine drugs. 2018, 16, 326.
15. Liqing Deng, Siyu Zhou, Jinxin Mao, Shuang Liu, Xiaozhong Lan, Zhihua Liao and Min Chen*. HPLC-ESI-MS/MS analysis of phenolics and in vitro antioxidant activity of Epilobium angustifolium L. Natural Product Research, 2018, 32(12), 1432-1435.
16. Jingxin Mao, Man Yia, Rui Wang, Yuanshe Huanga and Min Chen*. Protective Effects of Costunolide against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice. Frontiers in Pharmacology. 2018, 9: 1469 .
17. Wenrui Cao, jingqiu Ge, Xin Xie a, Menglin Fan, Xudong Fan, Hong Wang, Zhihua Liao, Xiaozhong Lan, and Min Chen*. Protective Effects of Petroleum Ether Extracts of Herpetospermum caudigerum on α-naphthylisothiocyanate-Induced Acute Cholestasis Rats. Journal of Ethnopharmacology. 2017, 198(1): 139-147.
18. Jingqiu Ge, Yijie Hu, Hongxia Wang, Yuanshe Huang, Peng Zhang, Zhihua Liao and Min Chen*. Profiling of Anthocyanins in transgenic purple-fleshed sweet potatoes by HPLC-MS/MS. Journal of the science of food and agriculture. 2017, 97, (14), 4995-5003.
19. Lina Deng, Rui Wang, Guowei Wang, Mingxu Liu, Guojian Liao, Zhihua Liao, and Min Chen*. Targeted Isolation of Sulfur-containing Metabolites from Lsr2-deletion Mutant Strain of Streptomyces roseosporus. RSC Advances, 2017, 7, 37771–37777.
20. SiYu Zhou, GuoWei Wang, YanLin Zou, Liqing Deng, Mingxu Liu, Zhihua Liao, Xiaozhong Lan, and Min Chen*. A new diphenyl ether derivative from Mirabilis himalaica. Natural Product Research. 2017, 31 (9): 1034-1041.
