Xiaoyan Zhao, PhD, Associate Professor in College of Pharmaceutical Sciences, Southwest University, No. 2 Tiansheng Road, Beibei, Chongqing, 400715, China
Email: zhaoxiaoyan67@163.com
Prof. Xiaoyan Zhao earned her PhD degree from Harbin Medical University in June 2009, and joined College of Pharmaceutical Sciences,Southwest University since then. She visited University of California, Los Angeles, USA from 2014 to 2015. She has a research expertise in cardiac pharmacology , antitumor drugs and antidiabetic drugs.
Research Interests
Cardiac pharmacology
Antitumor drugs
Antidiabetic drugs.
Selected Publications
1. Li DN, Song CZ, Zhang J, Zhao XY. ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo. Toxicology, 2022: 153113.
2. Song CZ, Li DN, Zhang J, Zhao XY. Role of ferroptosis in promoting cardiotoxicity induced by Imatinib Mesylate via down-regulating Nrf2 pathways in vitro and in vivo. Toxicology and applied pharmacology, 2022, 435: 115852.
3. Zeng Jie, Li Dongning, Li Zhubo; Zhang J, Zhao X. Dendrobium officinale Attenuates Myocardial Fibrosis via Inhibiting EMT Signaling Pathway in HFD/STZ-Induced Diabetic Mice. Biological & pharmaceutical bulletin. 2020; 43(5): 864-872.
4. Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, Zhao X. Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.J Biomed Nanotechnol. 2019 Feb 1;15(2):288-300.
5. Zhao X, Yang S, Zhang D, Li Z, Huang C. Arsenic Trioxide and Artemisinin Act Synergistically to Kill Tumor Cells In Vitro. Anticancer Agents Med Chem. 2018;18(15):2178-2186.
6. Zhao X, Dou M, Zhang Z, Zhang D, Huang C. Protective effect of Dendrobium officinale polysaccharides on H2O2-induced injury in H9c2 cardiomyocytes. Biomed Pharmacother. 2017;94:72-78.
7. Zhao X, Wang L, Zhang H, Zhang D, Zhang Z, Zhang J. Protective effect of artemisinin on chronic alcohol induced-liver damage in mice. Environ Toxicol Pharmacol. 2017 Apr; 52:221-226.
8. Zhang Z, Dou M, Yao X, Tang H, Li Z, Zhao X. Potential Biomarkers in Diagnosis of Human Gastric Cancer. Cancer Invest. 2016;34(3):115-22.
9. Dou M, Zhang Z, Li Z, Zhang J, Zhao X. Cardioprotective potential of Dendrobium offcinale Kimura et Migo against myocardial ischemia in mice. Mol Med Rep. 2016 Nov;14(5):4407-4414. doi: 10.3892/mmr.2016.5789.
10. Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X. Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice. Biomed Pharmacother. 2016 Oct; doi: 10.1016/j.biopha.2016.10.074.
11. He X, Huang Ｌ, Lu Y, Dou M, Zhang Z, Li Z, Zhang J, Zhao X. The Protective Effects of Artemisinin on Penicillin Sodium-Induced Epileptic Seizures in Mice. Lat. Am. J. Pharm. 2016 Mar; 35 (Suppl. 1): 1241-7.
12. Zhao XY, Yang S, Chen YR, Li PC, Dou MM, Zhang J. Resveratrol and arsenic trioxide act synergistically to kill tumor cells in vitro and in vivo. PLoS One. 2014 Jun 5; 9(6):e98925.
13. Li PC, Yang S, Dou MM, Chen YR, Zhang J, Zhao XY. Synergic effects of artemisinin and resveratrol in cancer cells. Journal of Cancer Research and Clinical Oncology. 2014, Jul 22; 140(12):2065-75.
14. Chen Y, Li P, Yang S, Tong N, Zhang J, Zhao X. Tetrandrine enhances the anticancer effects of arsenic trioxide in vitro. Int J Clin Pharmacol Ther. 2014 May;52(5):416-24.
15. Zhang J, Tong NN, Chen YR, Li PC, Yang S, Zhao XY. Resveratrol protects against vinorelbine-induced vascular endothelial cell injury. Toxicol Mech Methods. 2013 Nov;23(9):665-71.
16. Zhao XY, Zhang J, Tong NN, Chen YR, Luo YH. Protective effects of berberine on doxorubicin-induced hepatotoxicity in mice. Biological and Pharmaceutical Bulletin. 2012; 35(5):796-800.
17. Tong NN, Zhang J, Chen YR, Li ZB, Luo YH, Zuo H, Zhao XY. Berberine sensitizes mutliple human cancer cells to the anticancer effects of doxorubicin in vitro. Oncology Letters; 2012; 3(6):1263-1267.
18. Zhao XY, Zhang J, Tong NN, Liao XG, Wang EB, Li ZB, Luo YH, Zuo H. Berberine attenuates doxorubicin-induced cardiotoxicity in mice.The Journal of International Medical Research. 2011; 39(5):1720-1727.
19. Zhao XY, Qiao GF, Li BX, Chai LM, Li Z, Lu YJ, Yang BF. Hypoglycemic and hypolipidemic effects of emodin and its Influence on L-type Calcium Channels in dyslipidemic-diabetic rats. Clinical and Experimental Pharmacology and Physiology. 2009 Jan;36(1):29-34.
20. Zhao XY, Feng TM, Chen H, Shan HL, Zhang Y, Lu YJ, Yang BF. Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity. Basic Clin Pharmacol Toxicol. 2008 May;102(5):419-25.
21. Zhao XY, Li GY, Liu Y, Chai LM, Chen JX, Zhang Y, Lu YJ, Yang BF. Resveratrol protects against arsenic trioxide-induced cardiotoxicity in vitro and in vivo. Br J Pharmacol. 2008 May;154(1):105-13.
